AIMC Topic: Humans

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Practical applications of artificial intelligence chatbots in obstetrics and gynecology medical education.

American journal of obstetrics and gynecology
Generative artificial intelligence chatbots are sophisticated conversational artificial intelligence tools that have the capability to interpret natural language inputs and produce responses that closely resemble human speech. Artificial intelligence...

Machine Learning-Based Diagnostic Prediction Model Using T1-Weighted Striatal Magnetic Resonance Imaging for Early-Stage Parkinson's Disease Detection.

Academic radiology
RATIONALE AND OBJECTIVES: Diagnosing Parkinson's disease (PD) typically relies on clinical evaluations, often detecting it in advanced stages. Recently, artificial intelligence has increasingly been applied to imaging for neurodegenerative disorders....

A random forest-based predictive model for classifying BRCA1 missense variants: a novel approach for evaluating the missense mutations effect.

Journal of human genetics
The right classification of variants is the key to pre-symptomatic detection of disease and conducting preventive actions. Since BRCA1 has a high incidence and penetrance in breast and ovarian cancers, a high-performance predictive tool can be employ...

ULK2 deficiency stratifies autophagy-driven molecular subtypes and exacerbates trophoblasts apoptosis in preeclampsia.

Placenta
INTRODUCTION: Preeclampsia (PE), a placenta-originated hypertensive disorder of pregnancy, lacks targeted therapies despite its significant contribution to maternal and fetal morbidity. Emerging evidence implicates autophagy dysregulation in PE patho...

Functional connectivity anomalies in medication-naive children with ADHD: Diagnostic potential, symptoms interpretation, and a mediation model.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: To identify reliable electroencephalography (EEG) biomarkers for attention deficit/hyperactivity disorder (ADHD) by investigating anomalous functional connectivity patterns and their clinical relevance.

From marker to markerless: Validating DeepLabCut for 2D sagittal plane gait analysis in adults and newly walking toddlers.

Journal of biomechanics
The use of 3D marker-based motion analysis systems is considered the gold standard for tracking limb movements. However, these systems are expensive, limited to laboratory settings, and difficult to apply when studying paediatric populations. Therefo...

Artificial neural network model enhancing the accuracy of clinical evaluation for high-risk population of lymph node metastasis in non-intestinal type early gastric cancer: a multicenter real-world study in China.

International journal of surgery (London, England)
BACKGROUND: Recent years have witnessed a proliferation of studies aimed at developing clinical models capable of predicting lymph node metastasis (LNM) in early gastric cancer (EGC), yet tools for prediction grounded in the Lauren classification rem...

Updated perspectives on visceral pleural invasion in non-small cell lung cancer: A propensity score-matched analysis of the SEER database.

Current problems in cancer
BACKGROUND: Visceral pleural invasion (VPI), including PL1 (the tumor invades beyond the elastic layer) and PL2 (the tumor extends to the surface of the visceral pleura), plays a crucial role in staging Non-Small Cell Lung Cancer (NSCLC). However, th...

Two-step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments.

Medical physics
BACKGROUND: In partial arc volumetric modulated arc therapy (VMAT) for treating breast cancer, setting up the limiting gantry positions of the treatment machine is a nontrivial yet repetitive and time-consuming task during planning. Templatized solut...

Comprehensive evaluation and application of tissue clearing techniques for 3-D visualization of splenic neural and immune architecture.

American journal of physiology. Cell physiology
As the largest secondary lymphoid organ, the spleen plays a crucial role in initiating and sustaining immune responses against blood-borne pathogens through antigen capture and delivery. It is innervated by both autonomic and sensory nerves, which al...