AIMC Topic: Leukocyte Count

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Utilization of a Digital Automated Cell Morphology Analyzer Results for Determining Differential White Blood Cell Counts in a Turkish Pediatric Population.

The journal of applied laboratory medicine
BACKGROUND: Manual morphological analysis of peripheral blood smears (PBS) with light microscopy is an essential diagnostic and monitoring tool. Recently, automated morphology analyzers have been developed that can preclassify cells using artificial ...

Machine learning algorithms with body fluid parameters: an interpretable framework for malignant cell screening in cerebrospinal fluid.

Clinical chemistry and laboratory medicine
OBJECTIVES: This study aimed to develop and validate a machine learning (ML) model utilizing cerebrospinal fluid (CSF) body fluid parameters from hematology analyzers to screen for malignant cells.

Impact of analytical bias on machine learning models for sepsis prediction using laboratory data.

Clinical chemistry and laboratory medicine
OBJECTIVES: Machine learning (ML) models, using laboratory data, support early sepsis prediction. However, analytical bias in laboratory measurements can compromise their performance and validity in real-world settings. We aimed to evaluate how analy...

Augmentation of Infrared Microscopy of White Blood Cells and Medical Measures for Rapid and Accurate Diagnosis of Bacterial or Viral Infections in Febrile Pediatric Oncology Patients: An Expert System-Based Study.

Analytical chemistry
Infectious diseases, a major contributor to high mortality rates, often exhibit similar symptoms, despite variations in immune responses to bacterial or viral infections. Rapidly differentiating bacterial infections from viral infections in febrile p...

A prediction model for reactivation of Langerhans cell histiocytosis based on machine-learning algorithms.

European journal of dermatology : EJD
Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasm characterized by the clonal proliferation of myeloid progenitor cells. The reactivation rate of LCH exceeds 30%. However, an effective prediction model to predict reactivatio...

Increasing a microscope's effective field of view via overlapped imaging and machine learning.

Optics express
This work demonstrates a multi-lens microscopic imaging system that overlaps multiple independent fields of view on a single sensor for high-efficiency automated specimen analysis. Automatic detection, classification and counting of various morpholog...

Evaluation of Combined Cancer Markers With Lactate Dehydrogenase and Application of Machine Learning Algorithms for Differentiating Benign Disease From Malignant Ovarian Cancer.

Cancer control : journal of the Moffitt Cancer Center
BACKGROUND: The differential diagnosis of ovarian cancer is important, and there has been ongoing research to identify biomarkers with higher performance. This study aimed to evaluate the diagnostic utility of combinations of cancer markers classifie...

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes.

EBioMedicine
The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes i...

Physicochemical properties and biological evaluation of Yoyo bitters.

African journal of medicine and medical sciences
BACKGROUND: The current widespread distribution and use of Yoyo bitters; an herbal bitters made in Nigeria calls for an assessment of its content, efficacy and extent to which this product achieves the labelled claim of being an herbal cleanser.