AIMC Topic: Rats
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Development and validation of a bioanalytical method for quantification of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma using LC-MS/MS.
Journal of pharmaceutical and biomedical analysis
Dec 15, 2017
LNA-i-miR-221, a 13-mer oligonucleotide, is a new miR-221 inhibitor that could be used as a novel drug for multiple myeloma. Herein, an ion-pair reversed phase liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and va...
Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations: An Experimental Study.
The journal of international advanced otology
Dec 14, 2017
OBJECTIVE: We investigated the use of autologous platelet-rich plasma (PRP) to improve the success rate of fat graft myringoplasty in perforated tympanic membranes of rats.
Effects of aqueous leaf extract of Tridax procumbens on contractile activity of corpus cavernosum in N-nitro-l-arginine methyl ester-induced hypertensive male rats.
Journal of integrative medicine
Nov 26, 2017
OBJECTIVE: This study investigated the effects of aqueous leaf extract of Tridax procumbens (ALETP) on contractile activity of corpus cavernosum in N-nitro-l-arginine methyl ester (l-NAME)-induced hypertensive male rats.
Development and validation of an LC-MS/MS method for quantification of NC-8 in rat plasma and its application to pharmacokinetic studies.
Journal of food and drug analysis
Nov 11, 2017
ent-16-Oxobeyeran-19-N-methylureido (NC-8) is a recently synthesized derivative of isosteviol that showed anti-hepatitis B virus (HBV) activity by disturbing replication and gene expression of the HBV and by inhibiting the host toll-like receptor 2/n...
The role of neuron-glia interactions in the emergence of ultra-slow oscillations.
Biological cybernetics
Nov 11, 2017
Ultra-slow cortical oscillatory activity of 1-100 mHz has been recorded in human by electroencephalography and in dissociated cultures of cortical rat neurons, but the underlying mechanisms remain to be elucidated. This study presents a computational...
Inhibitory activity of phenolic-rich pistachio green hull extract-enriched pasta on key type 2 diabetes relevant enzymes and glycemic index.
Food research international (Ottawa, Ont.)
Nov 8, 2017
Phenolic compounds as agro-industrial by-products have been associated with health benefits since they exhibit high antioxidant activity and anti-diabetic properties. In this study, polyphenol-rich extract from pistachio green hull (PGH) was evaluate...
Specific chemiluminescent protocol for dual-site recognition of Streptococcus mutans utilizing strong affinity between teicoplanin and Gram-positive bacteria.
Talanta
Nov 6, 2017
A novel dual-site recognition protocol was developed for chemiluminescent (CL) detection of Streptococcus mutans (S. mutans) based on a designed antibiotic-affinity strategy. Teicoplanin, a broad-spectrum antibiotic against Gram-positive bacteria, wa...
Horseradish Peroxidase
Iodobenzenes
Dipeptides
Rats
Milk
Fresh Water
Cell Wall
Limit of Detection
Anti-Bacterial Agents
Teicoplanin
Magnetite Nanoparticles
Immunoglobulin G
Bacterial Proteins
Luminol
Animals
Luminescent Measurements
Humans
Streptococcus mutans
Hydrogen Peroxide
Saliva
Protein Binding
A new rat-compatible robotic framework for spatial navigation behavioral experiments.
Journal of neuroscience methods
Nov 4, 2017
BACKGROUND: Understanding the neural substrate of information encoding and processing requires a precise control of the animal's behavior. Most of what has been learned from the rodent navigational system results from relatively simple tasks in which...
Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat.
Journal of food and drug analysis
Sep 22, 2017
Tangeretin, 4',5,6,7,8-pentamethoxyflavone, is one of the major polymethoxyflavones (PMFs) existing in citrus fruits, particularly in the peels of sweet oranges and mandarins. Tangeretin has been reported to possess several beneficial bioactivities i...
Development of a highly sensitive and specific ELISA method for the determination of l-corydalmine in SD rats with monoclonal antibody.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Sep 14, 2017
l-Corydalmine (l-CDL) is a potent analgesic constituent of the traditional Chinese medicine, Rhizoma Corydalis. However, the pharmacokinetic process and tissue distribution of l-CDL in vivo are still unknown. Therefore, it is necessary to establish a...
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