AIMC Topic: RNA, Messenger

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Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Advances in experimental medicine and biology
Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show ...

LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns.

Oncotarget
Accumulating evidences suggest that long non-coding RNAs (lncRNAs) perform important functions. Genome-wide chromatin-states area rich source of information about cellular state, yielding insights beyond what is typically obtained by transcriptome pr...

Effect of Mast Cell Chymase on Activation, Proliferation and Transdifferentiation of Hepatic Stellate Cells.

Hepato-gastroenterology
BACKGROUND/AIMS: This work aims to observe the effects of mast cell (MC) chymase on activation, proliferation and transdifferentiation of hepatic stellate cells (HSCs) and to discuss the role of chymase in development of liver fibrosis.