AIMC Topic: Tumor Necrosis Factor-alpha
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Danhong huayu koufuye prevents deep vein thrombosis through anti-inflammation in rats.
The Journal of surgical research
Nov 11, 2015
BACKGROUND: Danhong huayu koufuye (DHK) has traditionally been used clinically for a long time in China. This study was to evaluate the effect of DHK in treating deep vein thrombosis (DVT) in rats and explore its possible mechanism.
Prediction of feature genes in trauma patients with the TNF rs1800629 A allele using support vector machine.
Computers in biology and medicine
Jun 9, 2015
BACKGROUND: Tumor necrosis factor (TNF)-α variant is closely linked to sepsis syndrome and mortality after severe trauma. We aimed to identify feature genes associated with the TNF rs1800629 A allele in trauma patients and help to direct them toward ...
Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine release, and estrogen-related signaling pathways.
Environmental toxicology
May 26, 2015
Bisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide range of adverse health outcomes for which inflammation has also been hypothesized as a potentially ...
Diethylhexyl Phthalate
NF-kappa B
Benzhydryl Compounds
Cell Migration Assays, Macrophage
Chemotaxis, Leukocyte
Cell Movement
Lipopolysaccharides
Phenols
Interleukin-1beta
Tumor Necrosis Factor-alpha
Cells, Cultured
Macrophages
Cytokines
Estradiol
Humans
Female
Inflammation
Middle Aged
Signal Transduction
Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases.
mAbs
Dec 1, 2025
Tumor necrosis factor-alpha (TNFα) is a key pro-inflammatory cytokine implicated in the pathogenesis of numerous inflammatory and autoimmune diseases, including rheumatoid arthritis, inflammatory bowel disease, and neurodegenerative disorders such as...
Big data-driven target identification by machine learning: DRD2 as a therapeutic target for psoriasis.
Journal of dermatological science
Jul 1, 2025
BACKGROUND: The development of medical treatments has traditionally relied on researchers leveraging scientific knowledge to hypothesize disease mechanisms and identify therapeutic agents. However, the depletion of novel therapeutic targets has becom...
Changes of plasma Rap1A levels in patients with in-stent restenosis after percutaneous coronary intervention and the underlying mechanisms.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Nov 28, 2023
OBJECTIVES: Percutaneous coronary intervention (PCI) is one of the most important treatments for coronary artery disease (CAD). However, in-stent restenosis (ISR) after PCI is a serious complication without effective measures for prevention and treat...
Anti-inflammatory and antibacterial activities of P. petiolosa (Christ) Ching ethyl acetate extract against S. aureus in mice.
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
P. petiolosa as a typical Chinese herbal medicine has been generally utilized as Chinese native medicine formulation for treatment of chronic bronchitis, bronchial asthma and pneumoconiosis. The objective of this study was to evaluate the anti-inflam...
Disease Models, Animal
Mice, Inbred BALB C
Plant Leaves
Anti-Inflammatory Agents
Anti-Bacterial Agents
Lung
Inflammation Mediators
Tumor Necrosis Factor-alpha
Plant Extracts
Nitric Oxide Synthase Type II
Pneumonia, Staphylococcal
Animals
Membrane Proteins
Polypodiaceae
Staphylococcus aureus
Acetates
Solvents
Bacterial Load
Heme Oxygenase-1
Effects of extracts from Chuanwu (Aconitum Carmichaelii) and Banxia (Rhizoma Pinelliae) on excisional wound healing in a rat's model.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Feb 1, 2019
OBJEVTIVE: To investigate the effects of extracts from Chuanwu (Aconitum Carmichaelii) and Banxia (Rhizoma Pinelliae) on the excisional wound healing in a rat's model.
[Effect of TNF-α on the ability of stem cells from human exfoliated deciduous teeth to promote osteoclastogenesis].
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Oct 1, 2018
PURPOSE: To investigate the effect of tumor necrosis factor-α (TNF-α) on the ability of stem cells from human exfoliated deciduous teeth (SHED) to promote osteoclastogenesis.
The Association Between Arthralgia and Vedolizumab Using Natural Language Processing.
Inflammatory bowel diseases
Sep 15, 2018
BACKGROUND: The gut-selective nature of vedolizumab has raised questions regarding increased joint pain or arthralgia with its use in inflammatory bowel disease (IBD) patients. As arthralgias are seldom coded and thus difficult to study, few studies ...
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