AIMC Topic: Platinum

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Cytotoxic response of platinum-coated gold nanorods in human breast cancer cells at very low exposure levels.

Environmental toxicology Apr 6, 2015
Because of unique optical behavior gold nanorods (GNRs) have attracted attention for the application in biomedical field such as bio-sensing, bio-imaging and hyperthermia. However, toxicological response of GNRs is controversial due to their differen...
Acetylcysteine Caspase 9 G1 Phase Cell Cycle Checkpoints Down-Regulation Up-Regulation Apoptosis Nanotubes Membrane Potential, Mitochondrial Reactive Oxygen Species Platinum Caspase 3 Humans Proto-Oncogene Proteins c-bcl-2 Breast Neoplasms Particle Size Female Real-Time Polymerase Chain Reaction MCF-7 Cells Gold RNA, Messenger
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Integrating bulk RNA-seq and scRNA-seq analyses with machine learning to predict platinum response and prognosis in ovarian cancer.

Scientific reports May 31, 2025
Platinum-based therapy is an integral part of the standard treatment for ovarian cancer. However, despite extensive research spanning several decades, the identification of dependable predictive biomarkers for platinum response in clinical practice h...
Gene Expression Profiling Ovarian Neoplasms Transcriptome Platinum Single-Cell Analysis Drug Resistance, Neoplasm Humans Female RNA-Seq Machine Learning Biomarkers, Tumor Single-Cell Gene Expression Analysis Prognosis Antineoplastic Agents Gene Expression Regulation, Neoplastic
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Deep learning based on ultrasound images to predict platinum resistance in patients with epithelial ovarian cancer.

Biomedical engineering online May 13, 2025
BACKGROUND: The study aimed at developing and validating a deep learning (DL) model based on the ultrasound imaging for predicting the platinum resistance of patients with epithelial ovarian cancer (EOC).
Female Aged Adult Humans Retrospective Studies Platinum Carcinoma, Ovarian Epithelial Middle Aged Drug Resistance, Neoplasm Deep Learning Ultrasonography ROC Curve Image Processing, Computer-Assisted Ovarian Neoplasms
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[The Use of Platinum-Based Chemotherapy for Esophageal Cancer Patients with Impaired Renal Function].

Gan to kagaku ryoho. Cancer & chemotherapy Dec 1, 2023
INTRODUCTION: The key drugs of first-line chemotherapy for metastatic esophageal cancer are 5-FU and cisplatin(CF). However, the treatment strategy for unfit patients of CF regimen remains controversial.
Esophageal Neoplasms Kidney Humans Fluorouracil Antineoplastic Combined Chemotherapy Protocols Platinum Retrospective Studies Cisplatin Kidney Function Tests Aged
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Micrometer-sized electrically programmable shape-memory actuators for low-power microrobotics.

Science robotics Mar 17, 2021
Shape-memory actuators allow machines ranging from robots to medical implants to hold their form without continuous power, a feature especially advantageous for situations where these devices are untethered and power is limited. Although previous wor...
Microtechnology Mechanical Phenomena Electricity Electrochemical Techniques Equipment Design Platinum Smart Materials Humans Oxidation-Reduction Robotics
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An 88-milligram insect-scale autonomous crawling robot driven by a catalytic artificial muscle.

Science robotics Aug 19, 2020
The creation of autonomous subgram microrobots capable of complex behaviors remains a grand challenge in robotics largely due to the lack of microactuators with high work densities and capable of using power sources with specific energies comparable ...
Alloys Thermodynamics Muscles Artificial Organs Biomimetic Materials Locomotion Platinum Biomimetics Insecta Biomechanical Phenomena Animals Robotics Catalysis Equipment Design
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An integrated design and fabrication strategy for entirely soft, autonomous robots.

Nature Aug 25, 2016
Soft robots possess many attributes that are difficult, if not impossible, to achieve with conventional robots composed of rigid materials. Yet, despite recent advances, soft robots must still be tethered to hard robotic control systems and power sou...
Hydrogen Peroxide Printing, Three-Dimensional Robotics Oxygen Catalysis Equipment Design Hardness Elasticity Platinum Logic Motion Printing Microfluidics
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