AIMC Topic: Tumor Suppressor Protein p53

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[Role of high mobility group protein B1 in 
IL-1α-induced endothelial cell senescence].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Dec 28, 2017
To explore the effect of interleukin-1α (IL-1α) on the senescence of human umbilical vein endothelial cells (HUVECs) and the function of high mobility group protein 1 (HMGB1).
 Methods: HUVECs were randomly divided into a control group, a IL-1α group...
Humans RNA, Messenger Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinase Inhibitor p16 HMGB1 Protein Human Umbilical Vein Endothelial Cells Sirtuin 1 Cellular Senescence Tumor Suppressor Protein p53 beta-Galactosidase Random Allocation Interleukin-1alpha
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[Effect of jianpi-jiedu formula on tumor angiogenesis-relevant genes expression in colorectal cancer].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Dec 28, 2016
To investigate the effect of the jianpi-jiedu formula (JPJD) on the expression of angiogenesis-relevant genes in colon cancer.
 Methods: Crude extract was obtained from JPJD by water extract method. The effect of JPJD crude extract on colon cancer ce...
Humans Colorectal Neoplasms Animals Gene Expression Profiling Cell Line, Tumor Signal Transduction Drugs, Chinese Herbal Blotting, Western TOR Serine-Threonine Kinases STAT3 Transcription Factor Vascular Endothelial Growth Factor A Neovascularization, Pathologic Tumor Suppressor Protein p53 Down-Regulation Up-Regulation Cathepsin B Cathepsins Hypoxia-Inducible Factor 1, alpha Subunit Integrin alpha Chains Receptors, Urokinase Plasminogen Activator Sphingomyelin Phosphodiesterase
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