AIMC Topic: Mice, Inbred C57BL

Clear Filters Showing 151 to 160 of 254 articles

Deep Learning-Based Segmentation and Quantification in Experimental Kidney Histopathology.

Journal of the American Society of Nephrology : JASN Nov 5, 2020
BACKGROUND: Nephropathologic analyses provide important outcomes-related data in experiments with the animal models that are essential for understanding kidney disease pathophysiology. Precision medicine increases the demand for quantitative, unbiase...
Animals Male Diagnosis, Computer-Assisted Deep Learning Image Processing, Computer-Assisted Neural Networks, Computer Algorithms Reproducibility of Results Kidney Glomerulus Translational Research, Biomedical Schiff Bases Pattern Recognition, Automated Periodic Acid Mice Kidney Disease Models, Animal Mice, Inbred C57BL Kidney Diseases
View on PubMed DOI

Machine learning-based data analytic approaches for evaluating post-natal mouse respiratory physiological evolution.

Respiratory physiology & neurobiology Sep 30, 2020
Respiratory parameters change during post-natal development, but the nature of their changes have not been well-described. The advent of commercially available plethysmographic instruments provided improved repeatability of measurements and standardi...
Machine Learning Tidal Volume Animals, Newborn Respiratory Physiological Phenomena Animals Respiratory System Mice Plethysmography Age Factors Mice, Inbred C57BL
View on PubMed DOI

A machine learning approach for magnetic resonance image-based mouse brain modeling and fast computation in controlled cortical impact.

Medical & biological engineering & computing Sep 21, 2020
Computational modeling of the brain is crucial for the study of traumatic brain injury. An anatomically accurate model with refined details could provide the most accurate computational results. However, computational models with fine mesh details co...
Finite Element Analysis Neural Networks, Computer Machine Learning Brain Computer Simulation Animals Image Processing, Computer-Assisted Magnetic Resonance Imaging Brain Injuries Mice, Inbred C57BL
View on PubMed DOI

A high throughput machine-learning driven analysis of Ca spatio-temporal maps.

Cell calcium Jul 28, 2020
High-resolution Ca imaging to study cellular Ca behaviors has led to the creation of large datasets with a profound need for standardized and accurate analysis. To analyze these datasets, spatio-temporal maps (STMaps) that allow for 2D visualization ...
Machine Learning Reproducibility of Results Animals Time Factors Mice, Inbred C57BL Calcium Automation Interstitial Cells of Cajal Stochastic Processes
View on PubMed DOI

Deep learning-based classification of the mouse estrous cycle stages.

Scientific reports Jul 16, 2020
There is a rapidly growing demand for female animals in preclinical animal, and thus it is necessary to determine animals' estrous cycle stages from vaginal smear cytology. However, the determination of estrous stages requires extensive training, tak...
Mice Mice, Inbred C57BL Epithelial Cells Area Under Curve Leukocytes Estrous Cycle Data Accuracy Vagina Animals Male Deep Learning ROC Curve Vaginal Smears Neural Networks, Computer Female Adult Sensitivity and Specificity Humans
View on PubMed DOI

Time-resolved neurotransmitter detection in mouse brain tissue using an artificial intelligence-nanogap.

Scientific reports Jul 9, 2020
The analysis of neurotransmitters in the brain helps to understand brain functions and diagnose Parkinson's disease. Pharmacological inhibition experiments, electrophysiological measurement of action potentials, and mass analysers have been applied f...
Mice Action Potentials Mice, Inbred C57BL Parkinson Disease Brain Mapping Machine Learning Brain Female Animals Single Molecule Imaging Serotonin Electric Conductivity Neurotransmitter Agents Norepinephrine Electrodes Nanotechnology Cerebral Cortex Dopamine Artificial Intelligence
View on PubMed DOI

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis.

Journal of visualized experiments : JoVE Jun 18, 2020
Glomerular cell death is a pathological feature of myeloperoxidase anti neutrophil cytoplasmic antibody associated vasculitis (MPO-AAV). Extracellular deoxyribonucleic acid (ecDNA) is released during different forms of cell death including apoptosis,...
Humans Animals Male Image Processing, Computer-Assisted Extracellular Traps Mice, Inbred C57BL Models, Biological DNA Supervised Machine Learning Biopsy Peroxidase Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Glomerulonephritis Kidney Glomerulus Extracellular Space
View on PubMed DOI

Automatization and improvement of μCT analysis for murine lung disease models using a deep learning approach.

Respiratory research May 24, 2020
BACKGROUND: One of the main diagnostic tools for lung diseases in humans is computed tomography (CT). A miniaturized version, micro-CT (μCT) is utilized to examine small rodents including mice. However, fully automated threshold-based segmentation an...
Mice, Inbred C57BL Lung Diseases Pattern Recognition, Automated Female Male Absorptiometry, Photon Animals Deep Learning X-Ray Microtomography Mice Lipopolysaccharides
View on PubMed DOI

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature.

eLife May 14, 2020
The transcriptional activation and repression during NK cell ontology are poorly understood. Here, using single-cell RNA-sequencing, we reveal a novel role for T-bet in suppressing the immature gene signature during murine NK cell development. Based ...
Regulatory-Associated Protein of mTOR T-Box Domain Proteins T-bet Transcription Factor Gene Expression Regulation Killer Cells, Natural Forkhead Box Protein O1 Mechanistic Target of Rapamycin Complex 2 Rapamycin-Insensitive Companion of mTOR Protein Transcriptome Mice, Inbred C57BL Single-Cell Analysis Mice, Knockout Machine Learning RNA-Seq Proto-Oncogene Proteins c-akt Phenotype Genotype Bone Marrow Cells Animals Cluster Analysis Gene Expression Profiling
View on PubMed DOI

Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.

Journal of neurophysiology Apr 29, 2020
This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice ( = 23) during wakefulness and during isoflurane anesthesia (1.3%). Using isoflurane anesthesia as an independent variable e...
Mice Machine Learning Anesthesia Adenosine Mice, Inbred C57BL Acetylcholine Animals Microdialysis Norepinephrine Male Nerve Net Unconsciousness Isoflurane Anesthetics, Inhalation Prefrontal Cortex Wakefulness
View on PubMed DOI
Popular Topics
Recent Journals