AIMC Topic: Alanine Transaminase

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Liver enzymes, alcohol consumption and the risk of diabetes: the Suita study.

Acta diabetologica Aug 16, 2022
AIM: We aimed to investigate the combined impact of liver enzymes and alcohol consumption on the diabetes risk.
Aspartate Aminotransferases Male Alcohol Drinking Diabetes Mellitus Ethanol Liver gamma-Glutamyltransferase Alanine Transaminase Humans Female Risk Factors
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Hepatic enzymes and immunoinflammatory response to Bio-C Temp bioceramic intracanal medication implanted into the subcutaneous tissue of rats.

Scientific reports Feb 18, 2022
Our purpose was to evaluate the biocompatibility and hepatotoxicity of a new bioceramic intracanal medicament, Bio-C Temp (BIO). The biological properties of BIO were compared with calcium hydroxide-based intracanal medicament (Calen; CAL), used as g...
Calcium Hydroxide Materials Testing Biocompatible Materials Alanine Transaminase Aspartate Aminotransferases Subcutaneous Tissue Animals Rats Liver Aluminum Oxide Prostheses and Implants Root Canal Filling Materials
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Application of a Machine Learning Technology in the Definition of Metabolically Healthy and Unhealthy Status: A Retrospective Study of 2567 Subjects Suffering from Obesity with or without Metabolic Syndrome.

Nutrients Jan 15, 2022
The key factors playing a role in the pathogenesis of metabolic alterations observed in many patients with obesity have not been fully characterized. Their identification is crucial, and it would represent a fundamental step towards better management...
Machine Learning Biomarkers Prognosis Retrospective Studies Female Risk Factors Obesity Adipose Tissue Humans Glycated Hemoglobin Adult Artificial Intelligence Alanine Transaminase Male Absorptiometry, Photon Middle Aged Obesity, Metabolically Benign Insulin-Like Growth Factor I Health Status Metabolic Syndrome
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Development of a paper-based analytical device for the colourimetric detection of alanine transaminase and the application of deep learning for image analysis.

Analytica chimica acta Oct 14, 2021
A paper-based colourimetric assay for the detection of alanine transaminase has been developed. In the presence of alanine transaminase, 2,4-dinitrophenyl hydrazine changes to pyruvate hydrazone leading to a colour change from pale yellow to dark yel...
Paper Alanine Transaminase Indicators and Reagents Humans Deep Learning Colorimetry
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Artificial Intelligence Predicts Severity of COVID-19 Based on Correlation of Exaggerated Monocyte Activation, Excessive Organ Damage and Hyperinflammatory Syndrome: A Prospective Clinical Study.

Frontiers in immunology Aug 27, 2021
BACKGROUND: Prediction of the severity of COVID-19 at its onset is important for providing adequate and timely management to reduce mortality.
COVID-19 Macrophages Cytokines Prospective Studies Biomarkers Prognosis Humans Diagnosis, Computer-Assisted Monocytes Support Vector Machine HMGB1 Protein L-Lactate Dehydrogenase Alanine Transaminase Female SARS-CoV-2 Male Middle Aged Severity of Illness Index Aspartate Aminotransferases
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Using Unsupervised Machine Learning to Identify Age- and Sex-Independent Severity Subgroups Among Patients with COVID-19: Observational Longitudinal Study.

Journal of medical Internet research May 27, 2021
BACKGROUND: Early detection and intervention are the key factors for improving outcomes in patients with COVID-19.
Emergency Service, Hospital Cell Count Lymphocytes Datasets as Topic L-Lactate Dehydrogenase Neutrophils Alanine Transaminase Longitudinal Studies Aspartate Aminotransferases Humans Cluster Analysis Spain COVID-19 Unsupervised Machine Learning Prognosis Triage Monocytes C-Reactive Protein
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Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Clinical journal of the American Society of Nephrology : CJASN Oct 8, 2020
BACKGROUND AND OBJECTIVES: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically identify sepsis-associated AKI subphenotypes using deep learning on routinely collected data in electronic health records.
Blood Urea Nitrogen Leukocyte Count Simplified Acute Physiology Score Glutamyl Aminopeptidase Comorbidity Deep Learning Sepsis Renal Dialysis United States Creatinine L-Lactate Dehydrogenase Acute Kidney Injury Alanine Transaminase Humans Electronic Health Records Bilirubin Phenotype Female Lactic Acid Databases, Factual Aged Liver Diseases Prognosis Male Middle Aged
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Predictive Estimates of Risks Associated with Type 2 Diabetes Mellitus on the Basis of Biochemical Biomarkers and Derived Time-Dependent Parameters.

Journal of computational biology : a journal of computational molecular cell biology Apr 17, 2019
Aspartate Aminotransferases Machine Learning Humans Biomarkers Risk Assessment Prognosis Big Data Female Blood Glucose Risk Factors Diabetes Mellitus, Type 2 Male Cholesterol Alanine Transaminase
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Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jan 29, 2019
BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have no or only small EVs. Endoscopic screening for EVs is therefore a potentially deferrable procedure t...
Liver Cirrhosis Mass Screening International Normalized Ratio Esophageal and Gastric Varices Ascites Creatinine Non-alcoholic Fatty Liver Disease Female Hemoglobins Aged Sodium Hepatic Encephalopathy Male Platelet Count Serum Albumin Middle Aged Hepatitis C, Chronic Humans Blood Urea Nitrogen Risk Assessment Machine Learning Endoscopy, Digestive System Alanine Transaminase Severity of Illness Index Prospective Studies Thrombocytopenia Aspartate Aminotransferases Bilirubin Liver Cirrhosis, Alcoholic Gastrointestinal Hemorrhage
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Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium Dec 5, 2018
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...
Liver Function Tests Diabetes Mellitus, Type 2 Aged Humans Fatty Liver Decision Trees Biomarkers Logistic Models Supervised Machine Learning Male Electronic Health Records Middle Aged Liver Cirrhosis Non-alcoholic Fatty Liver Disease Female Disease Progression Health Status Hepatitis Risk Factors Case-Control Studies Alanine Transaminase Cohort Studies Aspartate Aminotransferases
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