AIMC Topic: Kidney Function Tests

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Improving precision of glomerular filtration rate estimating model by ensemble learning.

Journal of translational medicine Nov 9, 2017
BACKGROUND: Accurate assessment of kidney function is clinically important, but estimates of glomerular filtration rate (GFR) by regression are imprecise.
Kidney Function Tests Data Interpretation, Statistical Quality Improvement Middle Aged Cohort Studies Models, Theoretical Renal Insufficiency, Chronic Glomerular Filtration Rate Humans Neural Networks, Computer Machine Learning Female Aged Adult Sensitivity and Specificity Male
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A new machine-learning method to prognosticate paraquat poisoned patients by combining coagulation, liver, and kidney indices.

PloS one Oct 19, 2017
The prognosis of paraquat (PQ) poisoning is highly correlated to plasma PQ concentration, which has been identified as the most important index in PQ poisoning. This study investigated the predictive value of coagulation, liver, and kidney indices in...
Herbicides Kidney Liver Function Tests Kidney Function Tests Humans Liver Machine Learning Blood Coagulation Prognosis Paraquat
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Prescription of Guideline-Recommended Implantable Cardioverter Defibrillator and Cardiac Resynchronization Therapy Among Patients Hospitalized With Heart Failure and Varying Degrees of Renal Function.

The American journal of cardiology Dec 18, 2016
Implantable cardioverter defibrillators (ICD) and cardiac resynchronization therapy (CRT) reduce mortality in many patients with heart failure (HF), but the current use and effectiveness of ICD/CRT in patients with chronic kidney disease (CKD) are un...
Defibrillators, Implantable Humans Demography Electric Countershock Biomarkers Aged Kidney Function Tests Female Male Heart Failure Hospitalization Middle Aged Cardiac Resynchronization Therapy United States Practice Guidelines as Topic Treatment Outcome Renal Insufficiency
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Comparison of Clinical Trajectories before Initiation of Renal Replacement Therapy between Diabetic Nephropathy and Nephrosclerosis on the KDIGO Guidelines Heat Map.

Journal of diabetes research Dec 29, 2015
This study investigated differences between the clinical trajectories of diabetic nephropathy and nephrosclerosis using the Kidney Disease: Improving Global Outcomes (KDIGO) heat map and the clinical characteristics between the two diseases at RRT in...
Aged Adult Male Middle Aged Disease Progression Diabetes Mellitus, Type 2 Diabetic Nephropathies Kidney Glomerular Filtration Rate Kidney Function Tests Humans Retrospective Studies Renal Replacement Therapy Female Serum Albumin Albuminuria Nephrosclerosis Biopsy Creatinine Nephrology Practice Guidelines as Topic
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Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study.

Clinical lymphoma, myeloma & leukemia Dec 21, 2015
INTRODUCTION: The present study evaluated the pharmacokinetics and safety of elotuzumab, a humanized IgG1 monoclonal antibody against signaling lymphocyte activation molecule-F7, combined with lenalidomide and dexamethasone, in patients with multiple...
Cytogenetic Analysis Retreatment Thalidomide Neoplasm Staging Dexamethasone Multiple Myeloma Lenalidomide Aged, 80 and over Adult Male Middle Aged Severity of Illness Index Antineoplastic Combined Chemotherapy Protocols Treatment Outcome Kidney Function Tests Antibodies, Monoclonal, Humanized Kidney Diseases Humans Female Aged
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Imatinib Increases Serum Creatinine by Inhibiting Its Tubular Secretion in a Reversible Fashion in Chronic Myeloid Leukemia.

Clinical lymphoma, myeloma & leukemia Dec 20, 2015
BACKGROUND: Monitoring renal function is important in imatinib-treated patients with chronic myeloid leukemia because serum creatinine may increase during the course of therapy. The mechanism of this increase and its reversibility on treatment cessat...
Kidney Tubules Leukemia, Myelogenous, Chronic, BCR-ABL Positive Creatinine Drug Substitution Imatinib Mesylate Aged Protein Kinase Inhibitors Young Adult Adult Male Humans Middle Aged Antineoplastic Agents Retrospective Studies Case-Control Studies Female Treatment Outcome Glomerular Filtration Rate Kidney Function Tests
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Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions.

European heart journal. Cardiovascular pharmacotherapy Dec 10, 2015
AIMS: Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic prop...
Snake Venoms Natriuretic Peptide, C-Type Natriuretic Peptides Receptors, Atrial Natriuretic Factor Renal Agents Humans Animals Male Dogs Drug Design HEK293 Cells Glomerular Filtration Rate Cyclic GMP Kidney Function Tests Dendroaspis Structure-Activity Relationship Natriuretic Agents
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A Soft Computing Approach to Kidney Diseases Evaluation.

Journal of medical systems Aug 27, 2015
Kidney renal failure means that one's kidney have unexpectedly stopped functioning, i.e., once chronic disease is exposed, the presence or degree of kidney dysfunction and its progression must be assessed, and the underlying syndrome has to be diagno...
Humans Neural Networks, Computer Decision Support Techniques Comorbidity Kidney Function Tests Kidney Diseases Diagnosis, Differential Chronic Disease Female Reproducibility of Results Risk Factors Male Middle Aged Acute Disease Health Behavior
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Unraveling Uncertainty: The Impact of Biological and Analytical Variation on the Prediction Uncertainty of Categorical Prediction Models.

The journal of applied laboratory medicine Mar 3, 2025
BACKGROUND: Interest in prediction models, including machine learning (ML) models, based on laboratory data has increased tremendously. Uncertainty in laboratory measurements and predictions based on such data are inherently intertwined. This study d...
Humans Machine Learning Kidney Function Tests Female Models, Statistical Sensitivity and Specificity Area Under Curve Male Emergency Service, Hospital ROC Curve Uncertainty Renal Insufficiency, Chronic
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[The Use of Platinum-Based Chemotherapy for Esophageal Cancer Patients with Impaired Renal Function].

Gan to kagaku ryoho. Cancer & chemotherapy Dec 1, 2023
INTRODUCTION: The key drugs of first-line chemotherapy for metastatic esophageal cancer are 5-FU and cisplatin(CF). However, the treatment strategy for unfit patients of CF regimen remains controversial.
Antineoplastic Combined Chemotherapy Protocols Humans Fluorouracil Kidney Function Tests Retrospective Studies Esophageal Neoplasms Aged Platinum Kidney Cisplatin
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