AIMC Topic: Rats
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Prediction of early metastatic disease in experimental breast cancer bone metastasis by combining PET/CT and MRI parameters to a Model-Averaged Neural Network.
Bone
Nov 13, 2018
Macrometastases in bone are preceded by bone marrow invasion of disseminated tumor cells. This study combined functional imaging parameters from FDG-PET/CT and MRI in a rat model of breast cancer bone metastases to a Model-averaged Neural Network (av...
Effect of the in vitro gastrointestinal digestion on free-phenolic compounds and mono/oligosaccharides from Moringa oleifera leaves: Bioaccessibility, intestinal permeability and antioxidant capacity.
Food research international (Ottawa, Ont.)
Nov 10, 2018
Moringa oleifera is a plant recognized for its compounds such as dietary fiber (oligosaccharides, amongst others) and polyphenols, with biological activities. These properties depend on bioactive compounds (BC) interactions with food matrix/digestion...
Placental CD4 T cells isolated from preeclamptic women cause preeclampsia-like symptoms in pregnant nude-athymic rats.
Pregnancy hypertension
Nov 2, 2018
Preeclampsia (PE), new onset hypertension during pregnancy, is associated with a proinflammatory profile compared to normal pregnancy (NP). We hypothesize that CD4 T cells from PE patient placentas cause PE symptoms during pregnancy compared to those...
Pre-Eclampsia
Arterial Pressure
Placentation
Rats, Nude
Vascular Endothelial Growth Factor Receptor-1
Rats
Enzyme-Linked Immunosorbent Assay
Disease Models, Animal
Humans
Placenta
Adult
Tumor Necrosis Factor-alpha
CD4-Positive T-Lymphocytes
Animals
Pregnancy
Real-Time Polymerase Chain Reaction
Female
Interleukin-17
Young Adult
Hypertonic Saline Modulates Heart Function and Myocardial Inflammatory Alterations in Brain-Dead Rats.
The Journal of surgical research
Oct 23, 2018
BACKGROUND: Brain death (BD) in potential organ donors is responsible for hemodynamic instability and organ hypoperfusion, leading to myocardial dysfunction. Hypertonic saline (HS) is a volume expander with positive effects on hemodynamics and immuno...
Seizure forecasting using single robust linear feature as correlation vector of seizure-like events in brain slices preparation in vitro.
Neurological research
Oct 17, 2018
Epilepsy is a neurological disorder affecting 50 million individuals globally. Modern research has inspected the likelihood of forecasting epileptic seizures. Algorithmic investigations are giving promising results for seizure prediction. Though most...
In vitro and in vivo resistance of Lactobacillus rhamnosus GG carried by a mixed pineapple (Ananas comosus L. Merril) and jussara (Euterpe edulis Martius) juice to the gastrointestinal tract.
Food research international (Ottawa, Ont.)
Oct 4, 2018
This study evaluated the viability of Lactobacillus rhamnosus GG (LGG) and its in vitro and in vivo resistance to the gastrointestinal tract (GIT) when carried by a mixed fermented pineapple and jussara juice. The effects of product ingestion on the ...
Automatic glomerular identification and quantification of histological phenotypes using image analysis and machine learning.
American journal of physiology. Renal physiology
Sep 26, 2018
Current methods of scoring histological kidney samples, specifically glomeruli, do not allow for collection of quantitative data in a high-throughput and consistent manner. Neither untrained individuals nor computers are presently capable of identify...
Humans
Machine Learning
Reproducibility of Results
Animals
Male
Diagnosis, Computer-Assisted
Rats
Software
Automation, Laboratory
Phenotype
Female
Pattern Recognition, Automated
Species Specificity
Mice, Transgenic
Disease Models, Animal
Biopsy
Mice, Inbred C57BL
Workflow
Kidney Diseases
Kidney Glomerulus
Predictive Value of Tests
Microscopy
Image Interpretation, Computer-Assisted
A deep convolutional neural network approach for astrocyte detection.
Scientific reports
Aug 27, 2018
Astrocytes are involved in various brain pathologies including trauma, stroke, neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, or chronic pain. Determining cell density in a complex tissue environment in microscopy images an...
Comparative study on the effects of cigarette smoke exposure, ethanol consumption and association: Behavioral parameters, apoptosis, glial fibrillary acid protein and S100β immunoreactivity in different regions of the rat hippocampus.
Alcohol (Fayetteville, N.Y.)
Aug 23, 2018
Exposure to cigarette smoke and ethanol are proposed to trigger neurotoxicity, apoptosis, and to impair neuronal signaling. However, it is little known how the combination of both might trigger astrogliosis and the morphological changes capable of af...
Estimation of neural connections from partially observed neural spikes.
Neural networks : the official journal of the International Neural Network Society
Aug 18, 2018
Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major mechanisms of...
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