AIMC Topic: Cell Line
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aqueous extract attenuates isoproterenol-induced cardiac hypertrophy through the ERK signalling pathway.
Pharmaceutical biology
Dec 1, 2020
CONTEXT: The pharmacological functions of Wall. ex Lindl. (Orchidaceae) in cardiac hypertrophy remains unclear.
Elucidating the interaction dynamics between microswimmer body and immune system for medical microrobots.
Science robotics
Jun 17, 2020
The structural design parameters of a medical microrobot, such as the morphology and surface chemistry, should aim to minimize any physical interactions with the cells of the immune system. However, the same surface-borne design parameters are also c...
A reference library for assigning protein subcellular localizations by image-based machine learning.
The Journal of cell biology
Mar 2, 2020
Confocal micrographs of EGFP fusion proteins localized at key cell organelles in murine and human cells were acquired for use as subcellular localization landmarks. For each of the respective 789,011 and 523,319 optically validated cell images, morph...
In vitro cytotoxic, antioxidant, antibacterial and antifungal activity of Saussurea heteromalla indigenous to Pakistan.
Pakistan journal of pharmaceutical sciences
Nov 1, 2019
Medicinal plants are proven to reveal vast promising potential providing novel drug candidates to combat health-related problems. The aim of current study is to discover new drug compounds with anti-anticancer, antioxidant, antibacterial and antifung...
In vitro study of the nephrotoxicity of total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones and emodin in monolayer human proximal tubular epithelial cells cultured in a transwell chamber.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Oct 1, 2019
OBJECTIVE: To examine changes in the morphology and physiological functions of human proximal tubular epithelial cells (HK-2 cells) caused by total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones (TDA) and emodin.
Microsoft makes splash in AI-enabled lab solutions.
Nature biotechnology
Aug 1, 2019
Combined multivariate analysis and machine learning reveals a predictive module of metabolic stress response in Arabidopsis thaliana.
Molecular omics
Dec 3, 2018
Abiotic stress exposure of plants induces metabolic reprogramming which is tightly regulated by signalling cascades connecting transcriptional with translational and metabolic regulation. Complexity of such interconnected metabolic networks impedes t...
Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Allium senescens Linn. (Liliaceae) (ASL) has been traditionally used in Korea and other Asian countries for improving digestive and liver functions.
L1000FWD: fireworks visualization of drug-induced transcriptomic signatures.
Bioinformatics (Oxford, England)
Jun 15, 2018
MOTIVATION: As part of the NIH Library of Integrated Network-based Cellular Signatures program, hundreds of thousands of transcriptomic signatures were generated with the L1000 technology, profiling the response of human cell lines to over 20 000 sma...
Measurement of the mechanical properties of single Synechocystis sp. strain PCC6803 cells in different osmotic concentrations using a robot-integrated microfluidic chip.
Lab on a chip
Apr 17, 2018
Synechocystis sp. strain PCC6803 (Synechocystis) is a model microorganism and its mechanosensitive (MS) channels play important roles in its osmoadaptation mechanism. When the osmotic concentration of the culture environment changes, the inner pressu...
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