AIMC Topic: Anti-Inflammatory Agents

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Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.

Atherosclerosis Dec 24, 2018
BACKGROUND AND AIMS: The neuropeptide catestatin (CST) is an endogenous nicotinic cholinergic antagonist that acts as pleiotropic cardiac protective hormone. This study investigated the association between CST and coronary artery disease (CAD) and th...
Angiotensin-Converting Enzyme 2 Cells, Cultured Chromogranin A Cytokines Mice, Knockout, ApoE Biomarkers Anti-Inflammatory Agents Peptidyl-Dipeptidase A Female Coronary Artery Disease Male Plaque, Atherosclerotic Animals Atherosclerosis Severity of Illness Index Down-Regulation Case-Control Studies Cell Adhesion Molecules Disease Models, Animal Humans Human Umbilical Vein Endothelial Cells Peptide Fragments
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Compatible stability of methylprednisolone sodium succinate and tropisetron in 0.9% sodium chloride injection.

European journal of hospital pharmacy : science and practice Dec 1, 2018
BACKGROUND: A combination of methylprednisolone sodium succinate and tropisetron hydrochloride is commonly used to treat the nausea and vomiting associated with antineoplastic therapy. The objective of this study was to investigate the stability of t...
Antiemetics Humans Drug Incompatibility Anti-Inflammatory Agents Chromatography, High Pressure Liquid Injections Methylprednisolone Hemisuccinate Drug Stability Saline Solution Tropisetron
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Jobelyn attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec 27, 2017
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the physical and psychosocial wellbeing of the patients and a major cause of work disability. Current drugs for its treatment only provide palliative effect, as cure for the dis...
Freund's Adjuvant Oxidative Stress Mice Arthritis, Rheumatoid Antioxidants Tumor Necrosis Factor-alpha Plant Extracts Interleukin-6 Inflammation Animals Anti-Inflammatory Agents Male Sorghum Quality of Life Arthritis, Experimental Behavior, Animal Nervous System Diseases Edema
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HHV-8-associated haemophagocytic lymphohistiocytosis in a patient with advanced AIDS.

BMJ case reports Dec 22, 2017
We present a patient with advanced AIDS admitted with recurrent shock of unclear aetiology, fevers, altered mental status and refractory cytopenias. His case posed a diagnostic challenge because evaluation of septic shock in the setting of advanced A...
Dexamethasone Fatal Outcome Herpesviridae Infections Herpesvirus 8, Human Lymphohistiocytosis, Hemophagocytic Acquired Immunodeficiency Syndrome Diagnosis, Differential CD4 Lymphocyte Count Humans Anti-Inflammatory Agents Male Bone Marrow Middle Aged Fever Shock, Septic
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Gastro-protective effect of edible plant Artemisia argyi in ethanol-induced rats via normalizing inflammatory responses and oxidative stress.

Journal of ethnopharmacology Dec 20, 2017
PHARMACOLOGICAL RELEVANCE: Artemisia argyi, a kind of ethnic drug, has a long-term use on gastric diseases and syndromes.
Anti-Inflammatory Agents Artemisia Plants, Medicinal Inflammation Mediators RAW 264.7 Cells Free Radicals Rats, Wistar Malondialdehyde Superoxide Dismutase Ethanol Disease Models, Animal Cytoprotection Phytotherapy Anti-Ulcer Agents Gastric Mucosa Stomach Ulcer Macrophages Animals Oxidative Stress Mice Antioxidants Plant Extracts
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Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas Dec 11, 2017
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LP...
Cytokines Reproducibility of Results Enzyme-Linked Immunosorbent Assay Apoptosis Lipopolysaccharides Cell Line Humans Ginsenosides Nephritis Anti-Inflammatory Agents Reactive Oxygen Species Phosphatidylinositol 3-Kinases Epithelial Cells Proto-Oncogene Proteins c-akt Cell Survival Analysis of Variance Protective Agents Kidney Tubules Blotting, Western Cell Migration Assays
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Antioxidants from diet or supplements do not alter inflammatory markers in adults with cardiovascular disease risk. A pilot randomized controlled trial.

Nutrition research (New York, N.Y.) Nov 2, 2017
Antioxidants have been reported to have anti-inflammatory effects, but there is a lack of research comparing food to supplement antioxidant sources. The aim of this study was to determine if increases in intake of foods naturally rich in antioxidants...
Vitamins Intercellular Adhesion Molecule-1 Ascorbic Acid Carotenoids Tocopherols Humans Dietary Supplements Chemokine CCL2 Double-Blind Method Single-Blind Method Middle Aged Anti-Inflammatory Agents Diet Pilot Projects Interleukin-6 Selenium Biomarkers Antioxidants Female Inflammation Adult Male Cardiovascular Diseases
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Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice.

Journal of food and drug analysis Apr 19, 2017
Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demon...
Cytokines Biomarkers Animals Male Oils, Volatile Mice Plant Extracts Inflammation Signal Transduction Plant Leaves NF-kappa B Endotoxins Anti-Inflammatory Agents Humans NLR Family, Pyrin Domain-Containing 3 Protein Inflammation Mediators Acrolein Cinnamomum
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The Essential Oils of Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities.

Oxidative medicine and cellular longevity Dec 18, 2016
The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the di...
Tumor Necrosis Factor-alpha Interleukin-6 Microbial Sensitivity Tests Oils, Volatile Enzyme-Linked Immunosorbent Assay Candida albicans Humans Anti-Infective Agents Anti-Inflammatory Agents Pseudomonas aeruginosa Lipopolysaccharides Gas Chromatography-Mass Spectrometry Cell Line Enterococcus faecalis Reactive Oxygen Species Saccharomyces cerevisiae Plant Roots Leuzea Interleukin-1beta Astrocytes
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INHIBITORY ACTIVITY OF MANGIFERIN ON PYLORI-INDUCED INFLAMMATION IN HUMAN GASTRIC CARCINOMA AGS CELLS.

African journal of traditional, complementary, and alternative medicines : AJTCAM Nov 23, 2016
BACKGROUND: Gastric cancer is a serious health issue caused by and claims more lives in developing and undeveloped countries. Hence, the need for a natural drug with several pharmacological activities with no adverse effect are highly recommended. T...
Helicobacter Infections Helicobacter pylori Xanthones Humans Cell Line, Tumor Tumor Necrosis Factor-alpha Interleukin-1beta Stomach Neoplasms Interleukin-8 NF-kappa B Anti-Inflammatory Agents Carcinoma
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