AIMC Topic: Middle Aged

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Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jan 29, 2019
BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have no or only small EVs. Endoscopic screening for EVs is therefore a potentially deferrable procedure t...
Creatinine Non-alcoholic Fatty Liver Disease Hemoglobins Sodium Platelet Count Gastrointestinal Hemorrhage Liver Cirrhosis Hepatitis C, Chronic Hepatic Encephalopathy Mass Screening Humans Alanine Transaminase International Normalized Ratio Serum Albumin Machine Learning Aspartate Aminotransferases Esophageal and Gastric Varices Blood Urea Nitrogen Female Prospective Studies Bilirubin Ascites Endoscopy, Digestive System Aged Liver Cirrhosis, Alcoholic Thrombocytopenia Male Middle Aged Risk Assessment Severity of Illness Index
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Machine Learning to Predict Delays in Adjuvant Radiation following Surgery for Head and Neck Cancer.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Jan 29, 2019
OBJECTIVE: To apply a novel methodology with machine learning (ML) to a large national cancer registry to help identify patients who are high risk for delayed adjuvant radiation.
Neoplasm Staging Time-to-Treatment Radiotherapy, Adjuvant Databases, Factual Female Carcinoma, Squamous Cell Aged Male Middle Aged Cohort Studies United States Socioeconomic Factors Head and Neck Neoplasms Predictive Value of Tests Humans Machine Learning Algorithms
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Robot-Assisted Versus Fluoroscopy-Guided Pedicle Screw Placement in Transforaminal Lumbar Interbody Fusion for Lumbar Degenerative Disease.

World neurosurgery Jan 29, 2019
OBJECTIVE: To compare the clinical accuracy and perioperative outcomes for pedicle screw placement in transforaminal lumbar interbody fusion (TLIF) between the robot-assisted (RA) technique and fluoroscopy-guided (FG) technique.
Spinal Fusion Lumbar Vertebrae Surgery, Computer-Assisted Pedicle Screws Lumbosacral Region Zygapophyseal Joint Middle Aged Robotics Robotic Surgical Procedures Neurodegenerative Diseases Fluoroscopy Humans Female Aged Adult Male
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A decision support tool for early detection of knee OsteoArthritis using X-ray imaging and machine learning: Data from the OsteoArthritis Initiative.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society Jan 29, 2019
This paper presents a fully developed computer aided diagnosis (CAD) system for early knee OsteoArthritis (OA) detection using knee X-ray imaging and machine learning algorithms. The X-ray images are first preprocessed in the Fourier domain using a c...
Osteoarthritis, Knee Middle Aged X-Rays Diagnosis, Computer-Assisted Bayes Theorem Humans Early Diagnosis Multivariate Analysis Machine Learning Female Aged Male
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Identification of Diabetic Patients through Clinical and Para-Clinical Features in Mexico: An Approach Using Deep Neural Networks.

International journal of environmental research and public health Jan 29, 2019
Diabetes is a chronic and noncommunicable but preventable disease that is affecting the Mexican population at worrying levels, being the first place in prevalence worldwide. Early diabetes detection has become important to prevent other health condit...
Humans Health Status Neural Networks, Computer Area Under Curve Middle Aged Female Early Diagnosis ROC Curve Adult Models, Theoretical Male Diabetes Mellitus Mexico
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Diagnosis of early gastric cancer based on fluorescence hyperspectral imaging technology combined with partial-least-square discriminant analysis and support vector machine.

Journal of biophotonics Jan 28, 2019
This study investigated the feasibility of using fluorescence hyperspectral imaging technology to diagnose of early-stage gastric cancer. Fluorescence spectral images of 76 patients who were pathologically diagnosed as non-atrophic gastritis, premali...
Support Vector Machine Early Detection of Cancer Least-Squares Analysis Discriminant Analysis Feasibility Studies Optical Imaging Humans Female Stomach Neoplasms Male Middle Aged
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The feasibility of using robotic technology to quantify sensory, motor, and cognitive impairments associated with ALS.

Amyotrophic lateral sclerosis & frontotemporal degeneration Jan 27, 2019
OBJECTIVE: We used the KINARM robot to quantify impairments in cognitive and upper-limb sensorimotor performance in a cohort of people with amyotrophic lateral sclerosis (ALS). We sought to study the feasibility of using this technology for ALS resea...
Humans Female Aged Male Middle Aged Case-Control Studies Task Performance and Analysis Upper Extremity Proprioception Cognitive Dysfunction Robotics Amyotrophic Lateral Sclerosis Feasibility Studies Psychomotor Performance
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A Deep Learning Algorithm to Quantify Neuroretinal Rim Loss From Optic Disc Photographs.

American journal of ophthalmology Jan 26, 2019
PURPOSE: To train a deep learning (DL) algorithm that quantifies glaucomatous neuroretinal damage on fundus photographs using the minimum rim width relative to Bruch membrane opening (BMO-MRW) from spectral-domain optical coherence tomography (SDOCT)...
Visual Field Tests Optic Nerve Diseases Photography Glaucoma, Open-Angle Bruch Membrane Intraocular Pressure Male Middle Aged Deep Learning Vision Disorders Area Under Curve Tomography, Optical Coherence Nerve Fibers Optic Disk Retinal Ganglion Cells Visual Fields Retrospective Studies Female Aged Aged, 80 and over Cross-Sectional Studies Humans Algorithms
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Prediction of skin dose in low-kV intraoperative radiotherapy using machine learning models trained on results of in vivo dosimetry.

Medical physics Jan 25, 2019
PURPOSE: The purpose of this study was to implement a machine learning model to predict skin dose from targeted intraoperative (TARGIT) treatment resulting in timely adoption of strategies to limit excessive skin dose.
Skin Organs at Risk Radiotherapy Dosage Intraoperative Care Mastectomy, Segmental In Vivo Dosimetry Aged, 80 and over Adult Breast Neoplasms Middle Aged Models, Statistical Humans Neural Networks, Computer Machine Learning Female Aged
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Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier.

Breast cancer research : BCR Jan 25, 2019
BACKGROUND: BRCA1-mutated cancers exhibit deficient homologous recombination (HR) DNA repair, resulting in extensive copy number alterations and genome instability. HR deficiency can also arise in tumors without a BRCA1 mutation. Compared with other ...
Humans Female Aged CpG Islands DNA Methylation Promoter Regions, Genetic DNA Copy Number Variations Receptors, Estrogen Receptors, Progesterone Breast BRCA1 Protein Homologous Recombination Survival Analysis Datasets as Topic Adult Breast Neoplasms Middle Aged Epigenomics Support Vector Machine
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