AIMC Topic: NF-kappa B

Clear Filters Showing 21 to 30 of 46 articles

Development of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling.

PLoS computational biology Dec 14, 2020
Developing an accurate first-principle model is an important step in employing systems biology approaches to analyze an intracellular signaling pathway. However, an accurate first-principle model is difficult to be developed since it requires in-dept...
Algorithms Signal Transduction Apoptosis Lipopolysaccharides Least-Squares Analysis NF-kappa B Neural Networks, Computer
View on PubMed DOI

Chestnut shells (Italian cultivar "Marrone di Roccadaspide" PGI): Antioxidant activity and chemical investigation with in depth LC-HRMS/MS rationalization of tannins.

Food research international (Ottawa, Ont.) Nov 20, 2019
In Italy a particularly valuable chestnut is "Marrone di Roccadaspide", a protected geographical indication (PGI) product, deriving from a Castanea sativa cultivar, typical of Salerno province in Campania region. As chestnut industrial processes yiel...
Nuts Tannins Triterpenes Glucosides Tandem Mass Spectrometry Ellagic Acid Flavonoids Calibration Humans Fagaceae Antioxidants Hydrolyzable Tannins Plant Extracts Proanthocyanidins Cell Proliferation Phenols Rationalization Reactive Oxygen Species Evaluation Studies as Topic NF-kappa B Italy
View on PubMed DOI

Grape Seed Proanthocyanidin Extract Inhibits Human Esophageal Squamous Cancerous Cell Line ECA109 via the NF-B Signaling Pathway.

Mediators of inflammation Dec 17, 2018
Esophageal squamous cell carcinoma is the most common type of squamous cell carcinoma. Grape seed proanthocyanidin extract (GSPE) is considered to exhibit anticancer activity against several different types of cancer. We aimed to determine whether GS...
Esophageal Squamous Cell Carcinoma Grape Seed Extract Humans Cell Survival Cell Line, Tumor Enzyme-Linked Immunosorbent Assay Caspase 3 Cell Proliferation NF-kappa B Signal Transduction Esophageal Neoplasms Cell Movement Proanthocyanidins Apoptosis
View on PubMed DOI

Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-B/p65 Signaling in Chronic Radiculitis Rats.

Pain research & management Dec 13, 2018
BACKGROUND: Oxygen/ozone therapy is a minimally invasive technique for the treatment of radiculitis from lumbar disc herniation. This study aimed at investigating whether intrathecal administration of low-concentration oxygen/ozone could attenuate ch...
Signal Transduction Cyclic Nucleotide Phosphodiesterases, Type 2 Animals NF-kappa B Hyperalgesia Male Radiculopathy Treatment Outcome Transcription Factor RelA Intervertebral Disc Displacement Rats, Wistar Disease Models, Animal Cyclic AMP Rats Oxygen Cyclic GMP Ozone
View on PubMed DOI

Candida albicans-derived mannoproteins activate NF-κB in reporter cells expressing TLR4, MD2 and CD14.

PloS one Dec 27, 2017
The ability of soluble C. albicans 20A (serotype A) mannoprotein (CMP) to serve as a ligand for toll-like receptor 4 (TLR4) and its co-receptors was examined using commercially available and stably-transfected HEK293 cells that express human TLR4, MD...
Tumor Necrosis Factor-alpha Glycosylation Candida albicans Lipopolysaccharides Membrane Glycoproteins Interleukin-8 Humans Transcription, Genetic Lymphocyte Antigen 96 NF-kappa B HEK293 Cells Lipopolysaccharide Receptors Toll-Like Receptor 4 Cyclooxygenase 2
View on PubMed DOI

Effects of docosahexaenoic acid on locomotor activity in ethanol-treated HIV-1 transgenic rats.

Journal of neurovirology Dec 19, 2017
Binge drinking affects the onset and progression of human immunodeficiency virus (HIV)-associated neurological disorders. The HIV-1 transgenic (HIV-1Tg) rat was created with a gag- and pol-deleted HIV-1 viral genome to mimic HIV-infected patients rec...
HIV-1 Docosahexaenoic Acids Locomotion Corpus Striatum Endotoxins Rats Disease Models, Animal Gene Expression NF-kappa B Interleukin-18 Binge Drinking Rats, Inbred F344 Maze Learning Rats, Transgenic Interleukin-6 Animals Male HIV Infections
View on PubMed DOI

Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Biochemical and biophysical research communications Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
Dose-Response Relationship, Drug NF-kappa B Osteogenesis RAW 264.7 Cells Osteoblasts Glycosides Animals Mice Signal Transduction RANK Ligand Cells, Cultured Mice, Inbred C57BL Macrophages
View on PubMed DOI

Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-B Pathway.

BioMed research international Dec 3, 2017
BACKGROUND: Garlic-derived S-allylmercaptocysteine (SAMC) has widely been used in many disease therapies. However, the potential effects and mechanism of SAMC on IL-1-stimulated chondrocytes are unclear.
Garlic Collagen Type II Tissue Inhibitor of Metalloproteinase-1 Humans Tumor Necrosis Factor-alpha NF-kappa B Signal Transduction Chondrocytes Interleukin-1beta Osteoarthritis Gene Expression Matrix Metalloproteinases Transcription Factor RelA Cysteine
View on PubMed DOI

Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice.

Journal of food and drug analysis Apr 19, 2017
Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demon...
Humans Cytokines Biomarkers Animals Male Oils, Volatile Mice Plant Extracts Inflammation Signal Transduction NLR Family, Pyrin Domain-Containing 3 Protein Plant Leaves Inflammation Mediators NF-kappa B Acrolein Anti-Inflammatory Agents Cinnamomum Endotoxins
View on PubMed DOI

Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
Gene Expression Regulation Proliferating Cell Nuclear Antigen Cyclooxygenase 2 Cartilage, Articular Matrix Metalloproteinase 3 Matrix Metalloproteinase 9 bcl-2-Associated X Protein Rats Chondrocytes Inflammation Saponins Signal Transduction Tumor Suppressor Protein p53 Primary Cell Culture Rats, Sprague-Dawley Apoptosis Animals Achyranthes Caspase 3 bcl-Associated Death Protein Male Anti-Inflammatory Agents, Non-Steroidal bcl-X Protein Plant Extracts Plant Roots Interleukin-1beta NF-kappa B
View on PubMed DOI
Popular Topics
Recent Journals