AIMC Topic: Progression-Free Survival

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Intensity harmonization techniques influence radiomics features and radiomics-based predictions in sarcoma patients.

Scientific reports
Intensity harmonization techniques (IHT) are mandatory to homogenize multicentric MRIs before any quantitative analysis because signal intensities (SI) do not have standardized units. Radiomics combine quantification of tumors' radiological phenotype...

Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments.

BMC medical genomics
BACKGROUND: Machine learning (ML) methods still have limited applicability in personalized oncology due to low numbers of available clinically annotated molecular profiles. This doesn't allow sufficient training of ML classifiers that could be used f...

Combining gene expression profiling and machine learning to diagnose B-cell non-Hodgkin lymphoma.

Blood cancer journal
Non-Hodgkin B-cell lymphomas (B-NHLs) are a highly heterogeneous group of mature B-cell malignancies. Their classification thus requires skillful evaluation by expert hematopathologists, but the risk of error remains higher in these tumors than in ma...

Image-Guided Robotic Radiosurgery for Treatment of Recurrent Grade II and III Meningiomas. A Single-Center Study.

World neurosurgery
OBJECTIVE: Stereotactic radiosurgery (SRS) has been increasingly applied for malignant meningiomas as an alternative to conventionally fractioned radiation therapy. We performed a retrospective analysis of an institutional patient cohort with maligna...

Survival outcome prediction in cervical cancer: Cox models vs deep-learning model.

American journal of obstetrics and gynecology
BACKGROUND: Historically, the Cox proportional hazard regression model has been the mainstay for survival analyses in oncologic research. The Cox proportional hazard regression model generally is used based on an assumption of linear association. How...

Distillation of the clinical algorithm improves prognosis by multi-task deep learning in high-risk Neuroblastoma.

PloS one
We introduce the CDRP (Concatenated Diagnostic-Relapse Prognostic) architecture for multi-task deep learning that incorporates a clinical algorithm, e.g., a risk stratification schema to improve prognostic profiling. We present the first application ...