AIMC Topic: Disease-Free Survival

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Artificial intelligence weights the importance of factors predicting complete cytoreduction at secondary cytoreductive surgery for recurrent ovarian cancer.

Journal of gynecologic oncology Apr 23, 2018
OBJECTIVE: Accumulating evidence support that complete cytoreduction (CC) at the time of secondary cytoreductive surgery (SCS) improves survival in patients affected by recurrent ovarian cancer (ROC). Here, we aimed to determine whether artificial in...
Humans Neural Networks, Computer Prognosis Retrospective Studies Female Neoplasm Recurrence, Local Disease-Free Survival Cytoreduction Surgical Procedures Reoperation Kaplan-Meier Estimate Neoplasm, Residual Aged Middle Aged Time Factors Treatment Outcome Ovarian Neoplasms Neoplasm Staging
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Unsupervised versus Supervised Identification of Prognostic Factors in Patients with Localized Retroperitoneal Sarcoma: A Data Clustering and Mahalanobis Distance Approach.

BioMed research international Apr 23, 2018
The aim of this report is to unveil specific prognostic factors for retroperitoneal sarcoma (RPS) patients by univariate and multivariate statistical techniques. A phase I-II study on localized RPS treated with high-dose ifosfamide and radiotherapy f...
Retroperitoneal Neoplasms Models, Statistical Sarcoma Humans Disease-Free Survival Machine Learning Clinical Trials as Topic Aged Prognosis Multivariate Analysis Adult Female Male Middle Aged Cohort Studies Cluster Analysis
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L1 Cell Adhesion Molecule and Its Soluble Form sL1 Exhibit Poor Prognosis in Primary Breast Cancer Patients.

Clinical breast cancer Dec 28, 2017
INTRODUCTION: The L1 cell adhesion molecule (L1-CAM) and its soluble form sL1 play a prominent role in invasion and metastasis in several cancers. However, its association with breast cancer is still unclear.
Disease-Free Survival Humans Cell Membrane Adult Prognosis Cytoplasm Breast Neoplasms Neural Cell Adhesion Molecule L1 Female Biomarkers, Tumor Aged Middle Aged Aged, 80 and over Disease Progression Lymphatic Metastasis
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Prognostic value of tumor volume in patients with head and neck squamous cell carcinoma treated with primary surgery.

Head & neck Dec 22, 2017
BACKGROUND: Tumor volume in head and neck squamous cell carcinoma (HNSCC) was mainly measured in nonsurgically treated patients. We analyzed the influence of tumor volume on complete response (CR), overall survival (OS), and clear surgical margins al...
Immunohistochemistry Biopsy, Needle Statistics, Nonparametric Margins of Excision Head and Neck Neoplasms Registries Disease-Free Survival Survival Analysis Tumor Burden Adult Male Humans Middle Aged Prognosis Risk Assessment Retrospective Studies Logistic Models Tomography, X-Ray Computed Squamous Cell Carcinoma of Head and Neck Female Aged
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Vitamin D deficiency and supplementation in patients with aggressive B-cell lymphomas treated with immunochemotherapy.

Cancer medicine Dec 22, 2017
Vitamin D deficiency has been reported to be a negative prognostic factor in elderly patients with aggressive B-cell lymphomas. In vitro data suggest that vitamin D supplementation may enhance rituximab-mediated cytotoxicity. We prospectively assesse...
Aged Lymphoma, Large B-Cell, Diffuse Male Middle Aged Immunotherapy Antineoplastic Combined Chemotherapy Protocols Treatment Outcome Vitamin D Vitamin D Deficiency Dietary Supplements Disease-Free Survival Doxorubicin Humans Female Cyclophosphamide Cholecalciferol Prednisone Rituximab Vincristine
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Optimal adjuvant endocrine treatment of ER+/HER2+ breast cancer patients by age at diagnosis: A population-based cohort study.

European journal of cancer (Oxford, England : 1990) Dec 21, 2017
BACKGROUND: Prior randomised controlled trials on adjuvant hormonal therapy included HER2 patients; however, a differential effect of aromatase inhibitors (AIs) versus tamoxifen (TAM) may have been missed in ER+/HER2+ patients that comprise 7-15% of ...
Aromatase Inhibitors Humans Kaplan-Meier Estimate Female Disease-Free Survival Receptors, Estrogen Aged Netherlands Antineoplastic Agents, Hormonal Adult Age of Onset Chemotherapy, Adjuvant Breast Neoplasms Receptor, ErbB-2 Tamoxifen Middle Aged Cohort Studies Proportional Hazards Models
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Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade.

Prostate cancer and prostatic diseases Dec 20, 2017
BACKGROUND: Patients with high-risk prostate cancer have an increased likelihood of experiencing a relapse following radical prostatectomy (RP). We previously conducted three neoadjuvant androgen-deprivation therapy (ADT) trials prior to RP in unfavo...
Follow-Up Studies Multicenter Studies as Topic Randomized Controlled Trials as Topic Prostatic Neoplasms Prostate Humans Neoplasm Staging Aged Androgen Antagonists Prostate-Specific Antigen Male Neoplasm Recurrence, Local Middle Aged Disease-Free Survival Treatment Outcome Prostatectomy Neoadjuvant Therapy Kallikreins
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Disease-free survival assessment by artificial neural networks for hepatocellular carcinoma patients after radiofrequency ablation.

Journal of the Formosan Medical Association = Taiwan yi zhi Jan 20, 2017
BACKGROUND/PURPOSE: Radiofrequency ablation (RFA) provides an effective treatment for patients who exhibit early hepatocellular carcinoma (HCC) stages or are waiting for liver transplantation. It is important to assess patients after RFA. The goal of...
Humans Disease-Free Survival Catheter Ablation Sensitivity and Specificity Male Neural Networks, Computer Liver Neoplasms Retrospective Studies Carcinoma, Hepatocellular Tomography, X-Ray Computed Treatment Outcome Female Taiwan Aged
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Efficacy according to blind independent central review: Post-hoc analyses from the phase III, randomized, multicenter, IPASS study of first-line gefitinib versus carboplatin/paclitaxel in Asian patients with EGFR mutation-positive advanced NSCLC.

Lung cancer (Amsterdam, Netherlands) Nov 30, 2016
OBJECTIVE: The Phase III, randomized, open-label IPASS study (NCT00322452) of first-line epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI) gefitinib versus carboplatin/paclitaxel for Asian patients with advanced non-small-cell lun...
Quinazolines Randomized Controlled Trials as Topic Neoplasm Staging Mutation Asian People Carboplatin Paclitaxel Disease-Free Survival Smoking ErbB Receptors Protein Kinase Inhibitors Gefitinib Middle Aged Antineoplastic Agents Humans Lung Neoplasms Female Antineoplastic Combined Chemotherapy Protocols Aged Adenocarcinoma Aged, 80 and over Carcinoma, Non-Small-Cell Lung Male
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Effect of Long-Term Hormonal Therapy (vs Short-Term Hormonal Therapy): A Secondary Analysis of Intermediate-Risk Prostate Cancer Patients Treated on NRG Oncology RTOG 9202.

International journal of radiation oncology, biology, physics Nov 8, 2016
PURPOSE: NRG Oncology RTOG 9202 was a randomized trial testing long-term adjuvant androgen deprivation (LTAD) versus initial androgen deprivation only (STAD) with external beam radiation therapy (RT) in mostly high-risk and some intermediate-risk pro...
Survival Rate Male Middle Aged Time Factors Treatment Outcome Adenocarcinoma Humans Retrospective Studies Aged Aged, 80 and over Radiotherapy, Conformal Drug Administration Schedule Risk Kaplan-Meier Estimate Antineoplastic Agents, Hormonal Prostatic Neoplasms Prostate-Specific Antigen Neoplasm Grading Androgen Antagonists Combined Modality Therapy Disease-Free Survival
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