AIMC Topic: Human Umbilical Vein Endothelial Cells
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Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.
Atherosclerosis
Dec 24, 2018
BACKGROUND AND AIMS: The neuropeptide catestatin (CST) is an endogenous nicotinic cholinergic antagonist that acts as pleiotropic cardiac protective hormone. This study investigated the association between CST and coronary artery disease (CAD) and th...
Human Umbilical Vein Endothelial Cells
Peptide Fragments
Anti-Inflammatory Agents
Coronary Artery Disease
Atherosclerosis
Male
Severity of Illness Index
Humans
Case-Control Studies
Cells, Cultured
Peptidyl-Dipeptidase A
Disease Models, Animal
Cytokines
Biomarkers
Down-Regulation
Plaque, Atherosclerotic
Female
Cell Adhesion Molecules
Animals
Angiotensin-Converting Enzyme 2
Chromogranin A
Mice, Knockout, ApoE
Robotic Patterning a Superhydrophobic Surface for Collective Cell Migration Screening.
Tissue engineering. Part C, Methods
Mar 27, 2018
Collective cell migration, in which cells migrate as a group, is fundamental in many biological and pathological processes. There is increasing interest in studying the collective cell migration in high throughput. Cell scratching, insertion blocker,...
Simvastatin and nanofibrous poly(l-lactic acid) scaffolds to promote the odontogenic potential of dental pulp cells in an inflammatory environment.
Acta biomaterialia
Dec 30, 2017
UNLABELLED: In this study, we investigated the anti-inflammatory, odontogenic and pro-angiogenic effects of integrating simvastatin and nanofibrous poly(l-lactic acid) (NF-PLLA) scaffolds on dental pulp cells (DPCs). Highly porous NF-PLLA scaffolds t...
Gene Expression Regulation
Odontogenesis
Humans
Human Umbilical Vein Endothelial Cells
Alkaline Phosphatase
Tissue Scaffolds
Biomarkers
Signal Transduction
Mesenchymal Stem Cells
Simvastatin
Young Adult
Lipopolysaccharides
Neovascularization, Physiologic
Cytoprotection
RNA, Messenger
Dental Pulp
Polyesters
Nanofibers
Inflammation
Cell Differentiation
Magnetically Coated Bioabsorbable Stents for Renormalization of Arterial Vessel Walls after Stent Implantation.
Nano letters
Dec 28, 2017
The insertion of a stent in diseased arteries is a common endovascular procedure that can be compromised by the development of short- and long-term inflammatory responses leading to restenosis and thrombosis, respectively. While treatment with drugs,...
Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dec 8, 2017
Atherosclerosis, the leading cause of cardiovascular diseases in the world, is a chronic inflammatory disorder characterized by the dysfunction of arteries. Oleanolic acid (OA) is a bioactive nature product which exists in various plants and herbs. P...
Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.
International journal of nanomedicine
Dec 30, 2016
Neovascularization (NV) of the cornea can disrupt visual function, causing ocular diseases, including blindness. Therefore, treatment of corneal NV has a high public health impact. Epigalloccatechin-3-gallate (EGCG), presenting antiangiogenesis effec...
Oligopeptides
Integrin alphaVbeta3
Corneal Neovascularization
Eye Burns
Ophthalmic Solutions
Hyaluronic Acid
Catechin
Molecular Targeted Therapy
Humans
Animals
Nanoparticles
Angiogenesis Inhibitors
Disease Models, Animal
Mice, Inbred C57BL
Cell Survival
Burns, Chemical
Human Umbilical Vein Endothelial Cells
Heat shock protein A12B protects against sepsis-induced impairment in vascular endothelial permeability.
The Journal of surgical research
Dec 30, 2015
BACKGROUND: As a common and life-threatening infectious syndrome, sepsis contributes significantly to morbidity and mortality in clinical settings. Vascular endothelial injury and hyperpermeability play an important role in the development of sepsis-...
Effect of Cell-Cell Interaction on Single-Cell Behavior Revealed by a Deep Learning-Aided High-Throughput Addressable Single-Cell Coculture System.
Analytical chemistry
May 13, 2025
Cell-cell interactions are crucial for understanding various physiological and pathological processes, yet conventional population-level methods fail to disclose the heterogeneity at a single-cell resolution. Single-cell coculture systems that isolat...
Changes of plasma Rap1A levels in patients with in-stent restenosis after percutaneous coronary intervention and the underlying mechanisms.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Nov 28, 2023
OBJECTIVES: Percutaneous coronary intervention (PCI) is one of the most important treatments for coronary artery disease (CAD). However, in-stent restenosis (ISR) after PCI is a serious complication without effective measures for prevention and treat...
Predicting enhancer-promoter interactions by deep learning and matching heuristic.
Briefings in bioinformatics
Jul 20, 2021
Enhancer-promoter interactions (EPIs) play an important role in transcriptional regulation. Recently, machine learning-based methods have been widely used in the genome-scale identification of EPIs due to their promising predictive performance. In th...
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