AIMC Topic: Cytokines

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Towards a new classification of stable phase schizophrenia into major and simple neuro-cognitive psychosis: Results of unsupervised machine learning analysis.

Journal of evaluation in clinical practice May 23, 2018
RATIONALE: Deficit schizophrenia, as defined by the Schedule for Deficit Syndrome, may represent a distinct diagnostic class defined by neurocognitive impairments coupled with changes in IgA/IgM responses to tryptophan catabolites (TRYCATs). Adequate...
Adult Male Middle Aged Quality of Life Psychiatric Status Rating Scales Humans Cytokines Female Cognitive Reserve Neurocognitive Disorders Neuroimmunomodulation Tryptophan Inflammation Schizophrenic Psychology Unsupervised Machine Learning Behavioral Symptoms Patient Acuity Schizophrenia Psychotic Disorders
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Identifying cytokine predictors of cognitive functioning in breast cancer survivors up to 10 years post chemotherapy using machine learning.

Journal of neuroimmunology Apr 19, 2018
INTRODUCTION: The purpose of this study is to explore 13 cytokine predictors of chemotherapy-related cognitive impairment (CRCI) in breast cancer survivors (BCS) 6 months to 10 years after chemotherapy completion using a multivariate, non-parametric ...
Cognitive Dysfunction Humans Machine Learning Cancer Survivors Cytokines Adult Female Breast Neoplasms Aged Cross-Sectional Studies Middle Aged Antineoplastic Agents
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Serum Levels of Visfatin, Omentin and Irisin in Patients with End-Stage Lung Disease Before and After Lung Transplantation.

Annals of transplantation Dec 26, 2017
BACKGROUND The aim of this study was to investigate serum concentrations of visfatin, irisin, and omentin in patients with end-stage lung diseases (ESLD) before and after lung transplantation (LTx) and to find relationship between adipokines levels a...
Lectins Adolescent Treatment Outcome Body Mass Index Idiopathic Pulmonary Fibrosis Nicotinamide Phosphoribosyltransferase Fibronectins GPI-Linked Proteins Lung Transplantation Cystic Fibrosis Postoperative Period Young Adult Adult Pulmonary Disease, Chronic Obstructive Male Middle Aged Humans Cytokines Female
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The Impact of Physical Activity on Serum Inflammatory Markers in Overweight Pubertal Boys: 24-Month Follow-Up Study.

Pediatric exercise science Dec 23, 2017
PURPOSE: To investigate the differences in the pattern of changes in serum inflammatory cytokines measured annually over a 24-month period, between less active and more active overweight boys.
Exercise Child Overweight Follow-Up Studies C-Reactive Protein Humans Cytokines Biomarkers Male Chemokine CCL2 Vascular Endothelial Growth Factor A Accelerometry Epidermal Growth Factor
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A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.

Nutrients Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Disease Models, Animal Metabolic Syndrome Dietary Supplements Liver Diet, High-Fat Lipids Coffea Non-alcoholic Fatty Liver Disease Alkaloids Diterpenes Insulin Time Factors Insulin Resistance Seeds Rats, Sprague-Dawley Caffeic Acids Cytokines Carbon-13 Magnetic Resonance Spectroscopy Animals Dietary Sucrose Blood Glucose
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Monitoring bottlenose dolphin leukocyte cytokine mRNA responsiveness by qPCR.

PloS one Dec 22, 2017
Both veterinarians caring for dolphins in managed populations and researchers monitoring wild populations use blood-based diagnostics to monitor bottlenose dolphin (Tursiops truncatus) health. Quantitative PCR (qPCR) can be used to assess cytokine tr...
Leukocytes Bottle-Nosed Dolphin Cytokines Animals Real-Time Polymerase Chain Reaction RNA, Messenger Cluster Analysis
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Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas Dec 11, 2017
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LP...
Ginsenosides Nephritis Reactive Oxygen Species Epithelial Cells Cell Survival Reproducibility of Results Protective Agents Blotting, Western Enzyme-Linked Immunosorbent Assay Humans Anti-Inflammatory Agents Apoptosis Cytokines Phosphatidylinositol 3-Kinases Lipopolysaccharides Proto-Oncogene Proteins c-akt Cell Line Analysis of Variance Kidney Tubules Cell Migration Assays
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Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec 8, 2017
Atherosclerosis, the leading cause of cardiovascular diseases in the world, is a chronic inflammatory disorder characterized by the dysfunction of arteries. Oleanolic acid (OA) is a bioactive nature product which exists in various plants and herbs. P...
Atherosclerosis Cell Survival Oleanolic Acid Rabbits Protective Agents Humans Up-Regulation Diet, High-Fat Receptors, Cytoplasmic and Nuclear Cytokines Angiotensins Lipoproteins, LDL Animals Cell Cycle Human Umbilical Vein Endothelial Cells Disease Models, Animal Apoptosis
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Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice.

Journal of food and drug analysis Apr 19, 2017
Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demon...
Inflammation Signal Transduction Plant Leaves NF-kappa B Anti-Inflammatory Agents Animals Humans Male Cytokines Oils, Volatile Biomarkers Mice NLR Family, Pyrin Domain-Containing 3 Protein Plant Extracts Inflammation Mediators Acrolein Cinnamomum Endotoxins
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Sensitive detection of rare disease-associated cell subsets via representation learning.

Nature communications Apr 6, 2017
Rare cell populations play a pivotal role in the initiation and progression of diseases such as cancer. However, the identification of such subpopulations remains a difficult task. This work describes CellCnn, a representation learning approach to de...
Neural Networks, Computer Cytokines Prognosis Single-Cell Analysis Monocytes Signal Transduction Humans T-Lymphocyte Subsets Rare Diseases Neoplasm, Residual Leukemia Acquired Immunodeficiency Syndrome Immunologic Memory Cytomegalovirus Infections Supervised Machine Learning Survival Analysis Killer Cells, Natural
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